The USC ADVANCE Study is a youth behavioral epidemiology research study that aims to better understand adolescent health and well-being.

About the ADVANCE Study

The ADVANCE Study collected school-based data on causes of teen social behavioral health issues among two cohorts of students (Class of 2024 and Class of 2025) throughout Southern California over their four years in high school. The study collected data from 11 schools, with approximately 4,500 students participating in the study.

As of 2025, both cohorts are being surveyed into adulthood. We hope to understand how health behavior patterns may change and fluctuate after students graduate from high school.

ADVANCE is currently in its 6th year of data collection, with a total of 10 high school waves and 1 young adult wave of data completed.

Our survey data provide an evidence-base to drive local policy change that protects youth and young adults from drug exposures and guides prevention programs that promote comprehensive well-being.

ADVANCE Study Timeline, Enrollments & Completions

USC ADVANCE number of enrollment (ENR), survey sample size (N), and completion rate (CR) from Wave 1 to Wave A.

Waves 9 and 10 include only the Class of 2025

Wave A is the first young adult wave and includes only the Class of 2024

Our Partners

Our study is funded by our partners:

    • NIH, U54CA180905-11, 2023-2028

    • NIH/NIDA, R01DA051843, 9/01/2020 – 8/31/2025

    • NIH/NCI, R01CA229617, 9/1/2019-8/31/2025

    • TRDRP, T33DT6620, 07/01/2023 - 06/30/2025

    • NIH/NCI, U54CA180905,​​ 7/19/2021-6/30/2024

    • NIH/NCI, Pilot Project, 9/1/2019-8/31/2023

    • NIH/FDA, U54CA180905, 9/1/2018-8/30/2023

    • NIH/NIDA, K01DA042950-04S1, 4/15/2021-8/31/2022

    • NIH/NIDA, K01DA042950, 9/1/2017-8/31/2022

Collaboration

Are you a researcher, interested in looking and using data collected from this study? Please click below to fill in the form! We will get back to you as soon as possible.

Publications

For a list of publications on the ADVANCE Study, click below!